ANTIBACTERIAL EFFICACY OF SOME LOCALLY PRODUCED DISINFECTANTS ON SOME CLINICAL ISOLATES

Abstract

The study aimed at evaluating the antibacterial efficacy of some locally produced disinfectants on some clinical isolates. The isolates obtained were identified through the morphology and biochemical tests. The organisms include Staphylococcus aureus, Klebsiella sp., Salmonella sp., and Escherichia coli. Antibacterial assay was carried out on test organisms using agar well diffusion method on Mueller Hinton agar and were incubated at 37°C for 24hours. The results showed zone of inhibition in diameter. For sample A, the zones of inhibition were 33mm, 35mm, 38mm, 28mm on Staphylococcus aureus, Klebsiella sp., Salmonella sp., and Escherichia coli respectively. Sample B was 20mm, 18mm, 27mm, and 30mm on Staphylococcus aureus, Klebsiella sp., Salmonella sp., and Escherichia coli respectively. Sample C had a zone of inhibition of 36mm, 25mm, 20mm, and 23mm on Staphylococcus aureus, Klebsiella sp., Salmonella sp., and Escherichia coli respectively. Sample D showed a zone of inhibition of 35mm, 32mm, 31mm, and 35mm on Staphylococcus aureus, Klebsiella sp., Salmonella sp., and Escherichia coli respectively. This result showed that sample A and D had more antibacterial effect against the Gram positive and Gram negative organisms used while sample B and C were less effective on them.